Published in bioRxiv, 2025
A free online dashboard for mining of mass spectrometry metabolomics data, automatically integrating orthogonal data on biological activity, sample metadata, and genomic information.
Published in Nucleic Acids Research, 2025
Update of the MIBiG database of biosynthetic gene clusters, with participation of 267 contributors in a global, collaborative effort.
Published in chemRxiv, 2024
Whitepaper for a data standard/repository for natural product-acting tailoring enzymes, which are essential for the biological activities of many specialized metabolites.
Published in Trends in Pharmacological Sciences, 2023
Review on genome- and metabolome-mining strategies for the investigation of ribosomally synthesized and post-translationally modified peptides (RiPPs).
Published in bioRxiv, 2022
Reports the prototype of a metabolomics dashboard for facilitating the prioritization of bioactive metabolite by integrating orthogonal data.
Published in Journal of Industrial Microbiology and Biotechnology, 2021
Perspective article on approaches for the natural product drug discovery from microbes in an industrial setting.
Published in Journal of Natural Products, 2021
In-depth investigation of 74 strain of the bacterial genus Planomonospora using mass spectrometry-based metabolomics and genomics, with the discovery of novel congeners of the antibiotic siomycin.
Published in Cell Chemical Biology, 2020
Discovery of the biarylitide class of natural products, encoded by the shortest known coding gene bytA of only 18 base pairs.
Published in bioRxiv, 2020
Discovery of the biarylitide class of natural products, encoded by the shortest known coding gene bytA of only 18 base pairs.
Published in bioRxiv, 2020
In-depth investigation of 74 strain of the bacterial genus Planomonospora using mass spectrometry-based metabolomics and genomics, with the discovery of novel congeners of the antibiotic siomycin.
Published in Chemical Data Collections, 2018
Rational investigation of the bacterial cell-wall forming enzyme MurD for novel inhibitory binding sites, using molecular docking with experimental validation.
Published in Nucleic Acids Research, 2025
Database on natural product-acting tailoring enzymes, which are essential for the biological activities of many specialized metabolites.
Published in chemRxiv, 2025
Database on natural product-acting tailoring enzymes, which are essential for the biological activities of many specialized metabolites.
Published in Analytical Chemistry, 2025
Comparative study on differences in metabolome mining strategies and annotation performance between different laboratories on the same dataset.
Published in Springer Metabolomics, 2025
Investigation of the impact of olive mill solid waste on the metabolic profile of medicinal fungi Hericium erinaceus and Pleurotus eryngii, using metabolome mining.
Published in Nucleic Acids Research, 2025
Update of the genome mining platform antiSMASH, with a focus on tailoring enzymes and terpenoids.
Published in Research Square, 2025
Investigation of the biosynthetic diversity of 111 lichen-associated fungi using genome and metabolome mining.
Published in Springer Metabolomics, 2025
In-depth metabolomics profiling of the plant Rumex sanguineus for food safety.
Published in chemRxiv, 2024
In-depth metabolomics profiling of the plant Rumex sanguineus for food safety.
Published in bioRxiv, 2024
Investigation of the impact of olive mill solid waste on the metabolic profile of medicinal fungi Hericium erinaceus and Pleurotus eryngii, using metabolome mining.
Published in Journal of Natural Products, 2021
Discovery of congeners of the Gq-inhibitor FR900359 using mass spectrometry-based metabolomics.
Published in Scientific Reports, 2021
Analysis of the biosynthetic capacity of Streptomyces sp. ID38640, the producer of the bacterial RNA polymerase inhibitor pseudouridimycin, using paired metabolomics and genomics analysis.
Published in Nucleic Acids Research, 2021
Update of the MIBiG database of biosynthetic gene clusters, with a focus on expanding non-ribosomal peptide synthetases.
Published in Journal of medicinal chemistry, 2016
Creation of the ProBiS plugin for PyMol and Chimera, a protein binding site alignment tool, and its use in the discovery of novel Mycobacterium tuberculosis InhA Inhibitors.